$$

From Simons panel at 44:50.

1. Alignment. Making sure there’s no funny reason the AI will go out of control.
2. Misuse. People using powerful AIs to advance their agendas.
3. Jobs. How do we organize as a society now that none of us have jobs? What do we do with our time?
4. Natural selection. How do things look like in the long run? Do we augment humans?